Risk of mortality according to the Charlson Comorbidity Index compared with the Frailty Index in elderly patients of the Centro Médico Naval between 2010 and 2015

Authors

DOI:

https://doi.org/10.24265/horizmed.2020.v20n4.09

Keywords:

Geriatrics, Comorbidity, Frail elderly, Mortality, Aging

Abstract

Objective: To quantify the risk of mortality using the Frailty Index, the Charlson Comorbidity Index and the Short Physical Performance Battery (SPPB) in elderly patients. Such three instruments are useful to assess and subsequently manage this group of patients. Materials and methods: An observational, cross-sectional and analytical study conducted from a secondary database analysis with a non-probability, convenience sampling. The database was collected from the original study “Prevalence and factors associated with frailty in Peruvian older adults” carried out between 2010 and 2015 in the Geriatrics Department of the Centro Médico Naval “Cirujano Mayor Santiago Távara.” A total of 1,897 participants over 60 years old were included. Results: Fragility values accounted for 51.33 %, 26.16 % and 73.47 %, according to the Frailty Index, the SPPB and the Charlson Comorbidity Index, respectively. The mortality rate in the study was 10.13 %. Conclusions: The three instruments compared in this study were significant to predict fragility. However, when a sexadjusted analysis was performed, the SPPB and the Charlson Comorbidity Index showed greater statistical significance.

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References

Chacón Cruzado MH, Parodi Freyre D. Riesgo de mortalidad según el índice de Charlson en comparación con el índice de fragilidad en pacientes adultos mayores del Centro Médico Naval entre los años 2010 al 2015 [Tesis de pregrado]. Lima: Universidad Científica del Sur. Facultad de Ciencias de la Salud; 2020.

Instituto Nacional de Estadística e Informática (INEI). Situación de la Población Adulta Mayor. Indicadores del adulto mayor trimestre: abril-mayo-junio 2018-Informe técnico [Internet]. 2019. Disponible en: https://www.inei.gob.pe/media/MenuRecursivo/boletines/informe-tecnico-situacion-de-la-poblacionadulta-mayor_dic2018.pdf

Lluis Ramos GE, Llibre Rodriguez JJ. Fragilidad en el adulto mayor: un primer acercamiento. Rev Cubana Med Gen Integr. 2004; 20(4).

Tello-Rodríguez T, Varela-Pinedo L. Frailty in older adults: detection, community-based intervention, and decision-making in the management of chronic illnesses. Rev Peru Med Exp Salud Publica. 2016; 33(2): 328-34.

Feinstein AR. The pre-therapeutic classification of comorbidity in chronic disease. J Chronic Dis. 1970; 23(7): 455-68.

Charlson M, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994; 47(11): 1245-51.

Iriarte E, Araya AX. Criterios de fragilidad en personas mayores que viven en la comunidad: una actualización de la literatura. Rev Med Chil. 2016; 144(11): 1440-7.

Chacón Betancourt EB, Mengana LO, Rodríguez Martorel DF, Arjona Rodríguez I, Leal Balón E, Cabrera Rojas I. Índice de CHARLSON como predictor de supervivencia tras un síndrome coronario agudo. Rev Cuba Cardiol Cir Cardiovasc. 2017; 23(2): 312-21.

Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001; 56(3): M146-56.

Hope AA, Ng Gong M. Discordance about frailty diagnosis between surrogates and physicians and its relationship to hospital mortality in critically ill older adults. J Frailty Aging. 2019; 8(4): 176-9.

Runzer-Colmenares FM, Samper-Ternet R, Al Snih S, Ottenbacher KJ, Parodi JF, Wong R. Prevalence and factors associated with frailty among peruvian older adults. Arch Gerontol Geriatr. 2014; 58(1): 69-73.

Runzer-Colmenares FM, Viñas-Mendieta A, Vela-Sosa R, Vasquez A, Cermeño-Maraví A, Moncada-Mapelli E, et al. Asociación entre submarinismo y trastornos neurocognitivos en personal militar retirado. Horiz Med. 2018; 18(1): 6-12.

Searle SD, Mitnitski A, Gahbauer EA, Gill TM, Rockwood K. A standard procedure for creating a frailty index. BMC Geriatr. 2008; 8: 24.

González N, Bilbao A, Forjaz MJ, Ayala A, Orive M, Garcia-Gutierrez S, et al. Psychometric characteristics of the spanish version of the barthel index. Aging Clin Exp Res. 2018; 30(5): 489-97.

Coelho T, Paúl C, Gobbens RJJ, Fernandes L. Frailty as a predictor of short-term adverse outcomes. Peer J. 2015; 3: e1121.

Rolfson DB, Majumdar SR, Tsuyuki RT, Tahir A, Rockwood K. Validity and reliability of the Edmonton Frail Scale. Age Ageing. 2006; 35(5): 526-9.

Washburn RA, Smith KW, Jette AM, Janney CA. The physical activity scale for the elderly (PASE): development and evaluation. J Clin Epidemiol. 1993; 46(2): 153-62.

Budson AE, Solomon PR. Memory Loss, Alzheimer's Disease, and Dementia. Chapter 2: Evaluating the patient with memory loss or dementia. 2011. pp. 5-38.

Urrunaga-Pastor D, Runzer-Colmenares FM, Arones TM, MezaCordero R, Taipe-Guizado S, Guralnik JM, et al. Factors associated with poor physical performance in older adults of 11 peruvian high andean communities. F1000Res. 2019; 8: 59.

Custodio N, Lira D. Adaptación peruana del Minimental State Examination (MMSE). An Fac Med. 2014; 75(1): 69.

Parodi JF, Nieto-Gutierrez W, Tellez WA, Ventocilla-Gonzales I, Runzer-Colmenares FM, Taype-Rondan A. Gait speed and the appearance of neurocognitive disorders in older adults: results of a peruvian cohort. Rev Esp Geriatr Gerontol. 2018; 53(2): 73-6.

Lozano Gallego M, Hernández Ferrándiz M, Turró Garriga O, Pericot Nierga I, López Pousa S, Vilalta Franch J. Validación del Montreal Cognitive Assessment (MoCA): test de cribado para el deterioro cognitivo leve. Datos preliminares. Alzheimer Real Invest Demen. 2009; 43: 4-11.

Buntinx F, Niclaes L, Suetens C, Jans B, Mertens R, Van den Akker M. Evaluation of Charlson’s comorbidity index in elderly living in nursing homes. J Clin Epidemiol. 2002; 55(11): 1144-7.

Romero-Ortuno R, Kenny RA. The frailty index in Europeans: association with age and mortality. Age Ageing. 2012; 41(5): 684-9.

Yang F, Gu D. Predictability of frailty index and its components on mortality in older adults in China. BMC Geriatr. 2016; 16: 145.

Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987; 40(5); 373-83.

Calvo E, Teruel L, Rosenfeld L, Guerrero C, Romero M, Romaguera R, et al. Frailty in elderly patients undergoing primary percutaneous coronary intervention. Eur J Cardiovasc Nurs. 2019; 18(2): 132-9.

Pereira AA, Arbex Borim FS, Neri AL. Absence of association between frailty index and survival in elderly Brazilians: the FIBRA Study. Cad Saúde Pública. 2017; 33(5): e00194115.

Rosas-Carrasco O, González-Flores E, Brito-Carrera AM, VázquezValdez OE, Peschard-Sáenz E, Gutiérrez-Robledo LM, et al. Evaluación de la comorbilidad en el adulto mayor. Rev Med Inst Mex Seguro Soc. 2011; 49(2): 153-62.

Benavides CL, García JA, Fernández JA, Rodrigues D, Ariza JF. Condición física, nivel de actividad física y capacidad funcional en el adulto mayor: instrumentos para su cuantificación. Rev. Actual Divulg Científica. 2017; 20(2): 255-65.

Abizanda P, Romero L. Age, frailty, disability, institutionalization, multimorbidity or comorbidity. J Nutr Heal Aging. 2014; 18(6): 622-7.

Published

2020-12-28

How to Cite

1.
Chacón-Cruzado MH, Parodi-Freyre D, Runzer-Colmenares FM, Parodi-García JF, Rojas-Jaimes J, De Noriega-Madalengoitia J. Risk of mortality according to the Charlson Comorbidity Index compared with the Frailty Index in elderly patients of the Centro Médico Naval between 2010 and 2015. Horiz Med [Internet]. 2020Dec.28 [cited 2025Jun.20];20(4):e1235. Available from: https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/1235

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Original article