Midazolam versus dexmedetomidine in sedation in gynecological surgery in the National Hospital Arzobispo Loayza 2015
DOI:
https://doi.org/10.24265/horizmed.2016.v16n2.08Keywords:
Sedation scale (SAS), Respiratory sedationAbstract
Objective: To determine the level of sedation and respiratory depression between midazolam and dexmedetomidine. Material and Methods: quantitative, observational, analytic, prospective study, experimental and inferential. Results: Sedation with midazolam was higher than the dexmedetomidine, with respect to respiratory depression using ANOVA test sp02 levels with midazolam were lower than the dexmedetomidine, p = 0.010 ,frequency variable and in amplexation variable with dexmedetomidine was decreased statistically significant with p < 0.001. Conclusions: Dexmedetomidine has sedative effects, without producing respiratory depression; the midazolam has a good sedative effect with some level of respiratory.
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Torress R, Fuentes Y, Cruz R. c comparación vs midazolam y dexmedetomidina en sedación intraoperatoria para extracción de catarata con anestesia local. Revista de Especialidades Médico-quirúrgicas 2005; 10 (1).
Aho M, Erkola A, et al. Comparison of dexmedetomidine and midazolam sedation and antagonism of dexmedetomidina with alipamezole. J Clin Anesth 1990;5,194-203.
Ribeiro VN, Júnior PDN. Uso de dexmedetomidina en Anestesiología. Rev Bras Anestesiol. 2003; 53: 1: 97- 113.
Ebert TJ. Effects of increasing plasma concentrations of dexmedetomidina. Anesthesiology 93:2. 2000; p382-94.
Bachand R, et al. Alpha 2 adrenergic agonist to prevent perioperative cardiovascular complications A meta-analysis. Am J Med 2003; 5: 114-119.
Tritsch AE, Welte M, von Homeyer P, et al. Bispectral index-guided sedation with dexmedetomidine I intensive care: a prospective, randomized, double blind, placebo-controlled phase II study. Crit care Med 2002;30:1007-1014.
Rewari V, Madan R, Kaul HL, Kumar I. Remifentanyl and propofol sedation for retrobulbar nerve block. Anaesth Intensive Care 2002;30:433-437.
Alhashemi JA. Dexmedetomidine versus midazolam for monitored anesthesia care during cataract surgery. Br J Anaesth 2006;96:722-726.
Hofer RE, Sprung J, Sarr MG, Wedel GJ. Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics. Can J Anaesth.
Tobias JD. Dexmedetomidine: applications in pediatric critical care and pediatric anesthesiology. Pediatr Crit Care Med. 2007;8:115-131.
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