Treatment of Staphylococcus aureus keratitis with 0.2% topical linezolid
DOI:
https://doi.org/10.24265/horizmed.2015.v15n3.08Keywords:
Bacterial keratitis, Staphylococcus aureus, Vancomycin, LinezolidAbstract
Objective: To reportthe use of 0.2% topical linezolid in the treatment of Staphylococcus aureuskeratitis with successful results. Material and Methods: All cases were viewed in Centro Vision, here they underwent a complete ophthalmic examination and were diagnosed with Staphylococcus aureus keratitis based on a microbiological study. In both cases we began with the gold standard therapy based on fortified topical drops of vancomycin and an aminoglycoside. Due to ineffective action and/or poor tolerance of vancomycin, we decided to use topical linezolid. Results: Two female patients with Staphylococcus aureus keratitis received ocular 0.2% topical linezolid every hour. In both cases we saw a marked clinical improvement and a good tolerance to this antibiotic. Conclusion: 0.2% Topical linezolid is an effective and well tolerated antibiotic when used in the treatment of Staphylococcus aureus keratitis. It is more comfortable and less toxic than topical vancomycin.
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