Preoperative testing for low- and intermediate-risk non-cardiac elective surgeries: a systematic review and cost-effectiveness analysis
DOI:
https://doi.org/10.24265/horizmed.2021.v21n3.13Keywords:
Preoperative period, Surgical procedures, operative, Practice guideline, Laboratory testAbstract
Preoperative tests are very common in daily clinical practice. However, ordering preoperative tests is not generally based on the best scientific evidence. When preoperative tests are ordered without justification, they may generate false-positive results, cause to repeat or order new tests and consultations, prolong hospital stay, result in problems to the patient (more risks, confusion and anxiety), and increase costs. A systematic review and cost-effectiveness analysis of preoperative tests for the most frequent low- and intermediate-risk non-cardiac elective surgeries performed at the Hospital Regional Lambayeque were conducted. According to the cost-effectiveness analysis, the annual cost of unnecessary preoperative tests amounts to S/ 62,778.00. However, if preoperative tests were adequately ordered and NICE guidelines were followed, their cost would decrease in 38.34 % (i.e., S/ 138.40 for each patient). The results show that preoperative tests should not be ordered for low- and intermediate-risk non-cardiac elective surgeries on a routinely basis. A thorough preoperative medical evaluation would safely decrease the need of other tests for this type of surgery.
Downloads
References
Edwards AF, Forest DJ. Preoperative laboratory testing. Anesthesiol Clin. 2018; 36(4): 493-507.
Smetana GW, Macpherson DS. The case against routine preoperative laboratory testing. Med Clin N Am. 2003; 87: 7-40.
Ibarra P. ¿Cuáles exámenes de laboratorio preanestésicos se necesitan en pacientes asintomáticos?. Rev Colomb Anestesiol. 2007; 35(4): 301-12.
Turnbull JM, Buck C. The value of preoperative screening investigations in otherwise healthy individuals. Arch Intern Med. 1987; 147: 1101-5.
Johnson RK, Mortimer AJ. Routine pre-operative blood testing: is it necessary?. Anaesthesia. 2002; 57: 914-7.
Contreras M. Evaluación médica preoperatoria como predictor de riesgo quirúrgico y no quirúrgico. Comunidad y Salud. 2010; 8(1): 83-96.
Rojas-Rivera W. Evaluación de los exámenes preoperatorios. Acta Méd Costarric. 2006; 48(4): 208-11.
Duddy C, Wong G. Explaining variations in test ordering in primary care: protocol for a realist review. BMJ Open. 2018; 8(9): e023117.
Ajimura FY, Maia ASSF, Hachlya A, Watanabe AS. Preoperative laboratory evaluation of patients aged over 40 years undergoing elective non cardiac surgery. São Paulo Med J. 2005; 123: 50-3.
Soares DS, Ribeiro BR, Nogueira MR, Fernandes de Azevedo VL, Vieira FA, Santana TE. Relevancia de los exámenes de rutina en pacientes de bajo riesgo sometidos a cirugías menores. Rev Bras Anestesiol. 2013; 63(2): 197-201.
Rajaram N, Karim HMR, Prakash A, Sahoo SK, Dhar M, Narayan A. Prevalence and impact of abnormal routine pre-operative test results among elective surgical patients with or without co-morbidity: an observational comparative study. Niger Postgrad Med J. 2018; 25(2): 121-5.
León-Jiménez F, Florián-Romero E, Caján-Lontop Y, Ventura-Sandoval L, Flores-Tucto M, Gastelo-Dávila A. Exámenes prequirúrgicos innecesarios y su costo en un hospital de Lambayeque. Acta Med Per. 2014: 31(2): 90-4.
Namoncura PC, Breinbauer KH. Utilidad y costo-efectividad de los exámenes preoperatorios en cirugía otorrinolaringológica. Rev Otorrinolaringol Cir Cabeza Cuello. 2009; 69: 117-24.
Fischer SP. Cost-effective preoperative evaluation and testing. Chest. 1999; 115: 96-100.
Narr BJ, Warner ME, Schroeder SR, Warner MA. Outcomes of patients with no laboratory assessment before anesthesia and a surgical procedure. Mayo Clin Proc. 1997; 72: 505-9.
Narr BJ, Hansen TR, Warner MA. Preoperative laboratory screening in healthy Mayo patients: cost-effective elimination of tests and unchanged outcomes. Mayo Clin Proc. 1991; 66: 155-9.
Li Wong JC. Costo efectividad en imagenología para el diagnóstico de enfermedad periodontal Centro Imaginológico Hanny X 2016 [Tesis]. Lima: Universidad San Martín de Porres. Facultad de Medicina Humana; 2017.
Guttikonda N, Nileshwar A, Rao M, Sushma TK. Preoperative laboratory testing-comparison of National Institute of Clinical Excellence guidelines with current practice -an observational study. J Anaesthesiol Clin Pharmacol. 2019; 35(2): 227-30.
Keshavan VH, Swamy CM. Pre-operative laboratory testing: a prospective study on comparison and cost analysis. Indian J Anaesth. 2016; 60(11): 838-42.
Karim HMR, Prakash A, Sahoo SK, Narayan A, Vijayan V. Abnormal routine pre-operative test results and their impact on anaesthetic management: An observational study. Indian J Anaesth. 2018; 62(1): 23-28.
Beloeil H, Ruchard D, Drewniak N, Molliex S. Overuse of preoperative laboratory coagulation testing and ABO blood typing: a french national study. Br J Anaesth. 2017; 119(6): 1186-93.
García-Miguel FJ, García Caballero J, Gómez de Caso-Canto JA. Indicaciones de la radiografía de tórax para la valoración preoperatoria en cirugía programada. Rev Esp Anestesiol Reanim. 2002; 49: 80-8.
García-Miguel FJ, García Caballero J, Gómez de Caso-Canto JA. Indications for electrocardiogram in the preoperative assessment for programmed surgery. Rev Esp Anestesiol Reanim. 2002; 49: 5-12.
Prieto L, Sacristána JA, Antoñanzas F, Rubio-Terrés C, Pintod JL, Rovirae J. Análisis coste-efectividad en la evaluación económica de intervenciones sanitarias. Med Clin (Barc). 2004; 122(13): 505-10.
Campillo-Artero C, Ortún V. El análisis de coste-efectividad: por qué y cómo. Rev Esp Cardiol. 2016; 69(4): 370-3.
Macpherson DS, Snow R, Lofgren RP. Preoperative screening: value of preoperative test. Ann Intern Med. 1990; 113: 969-73.
Roizen MF. Cost-effective preoperative laboratory testing. JAMA. 1994; 271: 319-20.
Balk EM, Earley A, Hadar N, Shah N, Trikalinos TA. Benefits and harms of routine preoperative testing: comparative effectiveness. Rockville (MD): Agency for Healthcare Research and Quality (US); 2014. Report No. 14.
Ranasinghe P, Perera YS, Senaratne JA, Abayadeera A. Preoperative testing in elective surgery: Is it really cost effective?. Anesth Essays Res. 2011; 5(1): 28-32.
Czoski-Murray C1, Lloyd Jones M, McCabe C, Claxton K, Oluboyede Y, Roberts J, et al. What is the value of routinely testing full blood count, electrolytes and urea, and pulmonary function tests before elective surgery in patients with no apparent clinical indication and in subgroups of patients with common comorbidities: a systematic review of the clinical and cost-effective literature. Health Technol Assess. 2012; 16(50): 1-159.
Morales-Orozco C, Mata-Miranda MP, Cárdenas-Lailson LE. Costo-beneficio de los exámenes preoperatorios de rutina en cirugía electiva. Cir Cir. 2005; 73(1): 25-30.
National Guideline Centre (UK). Preoperative tests (update): routine preoperative tests for elective surgery. London: National Institute for Health and Care Excellence (UK); 2016.
Feely MA, Collins CS, Daniels PR, Kebede EB, Jatoi A, Mauck KF. Preoperative testing before noncardiac surgery: guidelines and recommendations. Am Fam Physician. 2013; 87(6): 414-8.
Sociedad Argentina de Cardiología. Consenso de evaluación del riesgo cardiovascular en cirugía no cardiaca. Rev Argent Cardiol. 2005; 73(5): 381-96.
American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Practice advisory for preanesthesia evaluation:
Karim MR, Yunus M, Bhattacharyya P. An observational cohort study on pre-operative investigations and referrals: how far are we following recommendations?. Indian J Anaesth. 2016; 60(8): 552-9.
Leal-Mateos M, Madrigal-Solís JB. Analysis of preoperative test screening in patients undergoing elective surgery at the Gynecology Department of the “Rafael Angel Calderón Guardia” Hospital during 2009. Acta Méd Costarric. 2010; 52(3): 154-8.
Chung F, Yuan H, Yin L, Vairavanathan S, Wong DT. Elimination of preoperative testing in ambulatory surgery. Anesth Analg. 2009; 108(2): 467-75.
Schein OD, Katz J, Bass EB, Tielsch JM, Lubomski LH, Feldman MA, et al. The value of routine preoperative medical testing before cataract surgery. Study of Medical Testing for Cataract Surgery. N Engl J Med. 2000; 342(3): 168-75.
Benarroch-Gampel J, Sheffield KM, Duncan CB, Brown KM, Han Y, Townsend CM Jr, et al. Preoperative laboratory testing in patients undergoing elective, low-risk ambulatory surgery. Ann Surg. 2012; 256(3): 518-28.
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Horizonte Médico (Lima)

This work is licensed under a Creative Commons Attribution 4.0 International License.
Horizonte Médico (Lima) (Horiz. Med.) journal’s research outputs are published free of charge and are freely available to download under the open access model, aimed at disseminating works and experiences developed in biomedical and public health areas, both nationally and internationally, and promoting research in the different fields of human medicine. All manuscripts accepted and published in the journal are distributed free of charge under the terms of a Creative Commons license – Attribution 4.0 International (CC BY 4.0).