Bullous systemic lupus erythematosus in a 16-year-old male patient
DOI:
https://doi.org/10.24265/horizmed.2022.v22n3.11Keywords:
Lupus Erythematosus, Systemic, Lupus Erythematosus, Cutaneous, Blister, Lupus NephritisAbstract
Bullous systemic lupus erythematosus (BSLE) is a vesiculobullous disease mediated by autoantibodies in patients with systemic lupus erythematosus (SLE). Tense vesicles and bullae are seen on an edematous, erythematous and sometimes normal skin in any body region, including mucous membranes and non-photoexposed areas. This is the case of a 16-year-old male patient with lupus nephritis who, on the seventh day of hospitalization, presented multiple serous and hemorrhagic blisters on the face, trunk, abdomen and upper extremities. The histological study showed a subepidermal bullous
dermatosis with numerous neutrophils.
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References
Duan L, Chen L, Zhong S, Wang Y, Huang Y, He Y, et al. Treatment of
bullous systemic lupus erythematosus. J Immunol Res. 2015; 2015:
Navarro LMS, Poletti ED, Domínguez NVL, López SS, Delgado MAS.
Lupus eritematoso sistémico ampolloso: reporte de un caso y revisión
de la literatura. Dermatología CMQ. 2012; 10(3): 182-7.
Cardoza RJ, Castelar ME, Serpas LM, Muñoz M. Manifestaciones
clínicas e histopatológicas de lupus eritematoso sistémico bulloso en
un hospital de tercer nivel de atención. El Salvador, 2016. Unidad Inv
Cient. 2016.
Tincopa M, Puttgen KB, Sule S, Cohen BA, Gerstenblith MR. Bullous
lupus: an unusual initial presentation of systemic lupus erythematosus
in an adolescent girl. Pediatr Dermatol. 2010; 27(4): 373-6.
Charris EJE, Camargo JC, Siado JS, Buzon LC. Lupus ampolloso:
un verdadero reto diagnóstico y terapéutico. Biociencias. 2018;
(1): 123-36.
Rutnin S, Chanprapaph K. Vesiculobullous diseases in relation to lupus
erythematosus. Clin Cosmet Investig Dermatol. 2019; 12: 653-67.
Naranjo LAG, Duque GMV, Escobar MR. Enfermedad cutánea
ampollosa en el lupus eritematoso sistémico. Iatreia. 2012; 25(3):
-39.
De Risi-Pugliese T, Aubart FC, Haroche J, Moguelet P,
Grootenboer-Mignot S, Mathian A, et al. Clinical, histological,
immunological presentations and outcomes of bullous systemic lupus
erythematosus: 10 New cases and a literature review of 118 cases.
Semin Arthritis Rheum. 2018; 48(1): 83-9.
Contestable JJ, Edhegard KD, Meyerle JH. Bullous systemic lupus
erythematosus: a review and update to diagnosis and treatment. Am
J Clin Dermatol. 2014; 15(6): 517-24.
Żychowska M, Batycka-Baran A, Maj J, Baran W. Bullous systemic
lupus erythematosus associated with increased activity of lupus
nephritis: a case report and review of the literature. Postepy
Dermatol Alergol. 2018; 35(4): 431-3.
Odonwodo A, Vashisht P. Bullous systemic lupus erythematosus. In:
StatPearls. Treasure Island (FL): StatPearls Publishing; 2021.
Vargas GA, Gallego M, Carmona S. Lupus eritematoso sistémico
ampolloso con mejoría lenta con dapsona. Rev Asoc Colomb
Dermatol. 2016; 24(3): 211-5.
Vassileva S. Bullous systemic lupus erythematosus. Clin Dermatol.
; 22(2): 129-38.
Gharib K. Childhood bullous systemic lupus erythematosus: unusual
prognosis. Egypt J Dermatol Venerol. 2021; 41(1): 16-21.
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