Experience in the surgical treatment of juvenile nasopharyngeal angiofibroma at the Hospital de Especialidades No. 2 "Lic. Luis Donaldo Colosio Murrieta", Mexican Social Security Institute, Ciudad Obregón, Sonora
DOI:
https://doi.org/10.24265/horizmed.2018.v18n3.10Keywords:
Angiofibroma, Nasopharyngeal neoplasms, Recurrence, EmbolizationAbstract
Objective: To present our experience and assess the recurrence of juvenile nasopharyngeal angiofibroma after a surgical treatment (open versus endoscopic approach) in the country’s northwestern Department of Otorhinolaryngology. Materials and methods: An observational, retrospective, analytical study. The medical records of patients diagnosed with juvenile nasopharyngeal angiofibroma, who were treated at the Department of Otorhinolaryngology – Head and Neck Surgery of this institution from 2014 to 2017, were reviewed. Results: A total of 19 patients diagnosed with juvenile nasopharyngeal angiofibroma underwent a surgical procedure, out of which 14 had an open surgery and 5 an endoscopic one. Recurrence accounted for 50 % and 40 %, respectively, which was not statistically significant (p = 0.88). However, other variables were compared, such as the need for admission to the Intensive Care Unit (ICU), which was represented by 71 % in the case of the open approach and 20 % for the endoscopic approach, where a significant difference was found (p = 0.04). Conclusions: The study shows no statistically significant advantage of the endoscopic approach versus the open approach, but demonstrates less need for ICU admissions, which would reduce healthcare costs.
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Lamadrid-Bautista E, Guerrero-Espinoza D, González-Rull T, Azuara PE, Hernández OF. Angiofibroma juvenil nasofaríngeo: experiencia en un hospital general. An Orl Mex. 2013;58 (2):79-86.
Horcasitas-Pous R, Ordoñez-Solorio LA, Yee-Cota LD, Acosta López JR, Estrada Chavira E, Ramos Martínez E. La cirugía endoscópica en el tratamiento del angiofibroma nasofaríngeo juvenil: análisis de cinco casos. An Orl Mex. 2011; 56(4):155-161.
Ley-Mandujano SS, Campos-Navarro LA. Patrón histológico del nasoangiofibroma en pacientes del Centro Médico Nacional La Raza. An Orl Mex. 2014; 59:165-170.
Nicolai P, Schreiber A, Bolzoni Villaret A. Juvenile Angiofibroma: Evolution of Management. Int J Pediatr. 2012; 2012:1-11.
Bales C, Kotapka M, Loevner LA, Al-Rawi M, Weinstein G, Hurst R, et al. Craniofacial resection of advanced juvenile nasopharyngeal angiofibroma, Arch. Otolaryngol. Head Neck Surg. 2002; 128(9): 1071–1078.
Chul-Kee P, Dong Gyu K, Sun Ha P, Hyun-Tai C, Hee-Won J. Recurrent Juvenile Nasopharyngeal Angiofibroma Treated with Gamma Knife Surgery. J Korean Med Sci. 2006; 21(4):773-777.
Dong-Woo H, Ji-Hwan R, Yoo-Suk K, Kyu-Bo Kim, Won Shik K, Chang-Hoon K, et al. Treatment outcomes of juvenile nasopharyngeal angiofibroma according to surgical approach. Int J Pediatr Otorhinolaryngol. 2011; 75(1):69-73.
Borota L, Mahmoud E, Nyberg C, Ekberg T. Combined percutaneous and transarterial devascularisation of juvenile nasopharyngeal angiofibroma with protection of internal carotid artery: A modification of the technique. Interv Neuroradiol. 2015; 21(3):390-396.
Mishra S, Panigrahi R, Praveena N, Gupta YM. Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. J Clin Imaging Sci. 2013; 3:1.
Brandão Martins MB, Fontes de Lima FV, Mendonça CA, Passos Fiel de Jesus E, Granizo Santos AC, Prado Barreto VM, et al. Nasopharyngeal angiofibroma: Our experience and literature review. Int Arch Otorhinolaryngol. 2013; 17(1):14-19.
Schick B, Dlugaiczyk J, Wendler O. Expression of sex hormone receptors in juvenile angiofibromas and antiproliferative effects of receptor modulators. Head Neck. 2014;36(11):1596-1603.
Mallick S, Benson R, Bhasker S, Mohanti BK. Conformal radiotherapy for locally advanced juvenile nasopharyngeal angio-fibroma. J Can Res Ther. 2015; 11(1):73-77.
Panda NK, Gupta G, Sharma S, Gupta A. Nasopharyngeal Angiofibroma-changing Trends in the Management. Indian J Otolaryngol Head Neck Surg. 2012; 64(3):233-239.
Tiwari P, Teron P, Saikia N, Saikia HP, Bhuyan UT, Das D. Juvenile Nasopharyngeal Angiofibroma: A Rise in Incidence. Indian J Otolaryngol Head Neck Surg. 2015; 68(2):141-148.
Pryor S, Moore E, Kasperbauer J. Endoscopic versus Traditional Approaches for Excision of Juvenile Nasopharyngeal Angiofibroma. Laryngoscope. 2005; 115(7):1201-1207.
Andrade N, Pinto J, de Oliveira Nóbrega M, Aguiar JE, Aguiar TF, Vinhaes ES. Exclusively Endoscopic Surgery for Juvenile Nasopharyngeal Angiofibroma. Otolaryngol Head Neck Surg. 2007; 137(3):492-496.
Mohammadi Ardehali M, Samimi Ardestani S, Yazdani N, Goodarzi H, Bastaninejad S. Endoscopic approach for excision of juvenile nasopharyngeal angiofibroma: complications and outcomes. Am J Otolaryngol. 2010; 31:343-349.
Fyrmpas G, Konstantinidis I, Constantinidis J. Endoscopic treatment of juvenile nasopharyngeal angiofibromas: our experience and review of the literature. Eur Arch Otorhinolaryngol. 2011; 269(2):523-529.
Boghani, Z., Husain, Q., Kanumuri, Khan MN, Sangvhi S, Liu JK, et al. Juvenile nasopharyngeal angiofibroma: A Systematic Review and Comparison of Endoscopic, Endoscopic-Assisted, and Open Resection in 1047 Cases. Laryngoscope, 2013:123(4): 859–869.
Dahl J, Zopf D, Parikh S. Do open and endoscopic resection approaches to juvenile nasopharyngeal angiofibroma result in similar blood loss and recurrence rates?. Laryngoscope. 2015;125 (11):2436-2437.
Arens C. Transoral treatment strategies for head and neck tumors. GMS Curr Top Otorhinolaryngol Head Neck Surg. 2012;11:1-19.
Asser A. El Sharkawy. Endonasal endoscopic management of juvenile nasopharyngeal angiofibroma without angiographic embolization. Eur Arch Otorhinolaryngol. 2013; 270(7): 2051–2055.
Stapleton AL, Tyler-Kabara EC, Gardner PA, Snyderman CH. The Costs of Skull Base Surgery in the Pediatric Population. Journal of Neurological Surgery Part B, Skull Base. 2015;76(1):39-42.
Jones JW, Usman S, New J, Holcomb A, Gunewardena S, Tawfik O, et al. Differential Gene Expression and Pathway Analysis in Juvenile Nasopharyngeal Angiofibroma Using RNA Sequencing. Otolaryngol Head Neck Surg. 2018; (1).
Gupta R, Agarwal SP. Juvenile Nasopharyngeal Angiofibroma: Combined Approach for Excision, Transpalatal and Endoscopic; A New Perspective. Indian J Otolaryngol Head Neck Surg. 2018;70(1):125-129.
Song X, Wang D, Sun X, Wang J, Liu Z, Liu Q, et al, Cumulative sum analysis of the learning curve for endoscopic resection of juvenile nasopharyngeal angiofibroma, Surg Endosc. 2018;32(7):3181-3191.
Song X, Yang C, Zhang H, Wang J, Sun X, Hu L, et al. Hypoxia- Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis. Ann Otol Rhinol Laryngol. 2018; 127(6):357-366.
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