South American scientific research on the use of botulinum toxin in plastic surgery: a bibliometric analysis of articles indexed in Scopus
DOI:
https://doi.org/10.24265/horizmed.2024.v24n3.02Keywords:
Botulinum Toxins , Surgery, Plastic , Research , Publications , Latin AmericaAbstract
Objective: To analyze the scientific evolution of botulinum toxin usage in plastic surgery in Latin America. Materials and methods: A cross-sectional bibliometric study was conducted using Scopus as the data source. Visual and bibliometric analyses were performed, and metrics were generated to evaluate the evolution, general characteristics and
impact of the Latin American evidence on the use of botulinum toxin in plastic surgery. The bibliometrix R-package was utilized for this analysis. Results: The study included 34 documents published between 2002 and 2023, out of which 70.5 % (n = 24) were original articles and 23.5 % (n = 8) were reviews. International collaboration was identified in 32.3 % of the cases. The four most prolific authors were from Colombia and Brazil, each having published only two documents. Brazil (n = 20) was the most prolific country, followed by Chile (n = 5), Argentina (n = 4) and Colombia (n = 4). Regarding research trends, it was found that quality of life, dermal fillers, hyaluronic acid and wrinkles were the subtopics most related to the use of botulinum toxin in plastic surgery in Latin America. There were basically five associated research lines related to symptoms and
aesthetic procedures, cosmetic complications and quality of life. The degree of development of the topics essentially depended on aesthetic interventions. Multiple correspondence analysis based on authors’ keywords revealed that patient
follow-up, cohort studies, risk assessment, outcome evaluation, rejuvenation and adults are elements that primarily complement the base subtopics.
Conclusions: Slow growth with low production and impact has been identified in Latin American research on the use of botulinum toxin in plastic surgery over the last 20 years. This research has focused on clinical studies related to clinical outcome assessment, quality of life and aesthetic techniques. Brazil leads research in the region and maintains a strong
network of intercontinental collaboration.
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References
American Society of Plastic Surgeons. Botulinum toxin [Internet].
American Society of Plastic Surgeons: Illinois. Disponible en:
block,unwanted%20facial%20wrinkles%20or%20appearance
Freeman MD, Margulies IG, Sanati-Mehrizy P, Burish N, Taub PJ.
Nonaesthetic applications for botulinum toxin in plastic surgery. Plast
Reconstr Surg. 2020;146(1):157-70.
Noland ME, Lalonde DH, Yee GJ, Rohrich RJ. Current uses of
botulinum neurotoxins in plastic surgery. Plast Reconstr Surg.
;138(3):519e-530e.
Yu Y, Sun J, Shen Z, Lin X, Xu J. Auxiliary usage of botulinum toxin
A in plastic surgery in China. J Cosmet Dermatol [Internet]. 2020;
(5):1021-1028.
Noland ME, Morris SF. Botulinum toxin treatment in Plastic Surgery.
En: Jabbari B. Botulinum Toxin Treatment in Surgery, Dentistry, and
Veterinary Medicine. Connecticut: Springer Publishing Group; 2020.
-267.
Monheit G. Neurotoxins: Current concepts in cosmetic use on the face
and Neck--Upper face (Glabella, Forehead, and Crow's Feet). Plast
Reconstr Surg [Internet]. 2015;136(5):72-75.
Erickson BP, Lee WW, Cohen J, Grunebaum LD. The role of neurotoxins
in the periorbital and midfacial areas. Facial Plast Surg Clin North Am
[Internet]. 2015;23(2):243-55.
Safeek RH, Aslami Z, Azad CL. The role of plastic surgery in addressing the
global burden of disease: plastic surgery and the sustainable development
goals. Plast Reconstr Surg Glob Open [Internet]. 2023;11(5):90.
Lozada-Martinez ID, Visconti-Lopez FJ, Marrugo-Ortiz AC, Ealo-Cardona
CI, Camacho-Pérez D, Picón-Jaimes YA. Research and publication trends
in pediatric surgery in Latin America: a bibliometric and visual analysis
from 2012 to 2021. J Pediatr Surg [Internet]. 2023;58(10):2012-2019.
Yubo S, Ramayah T, Hongmei L, Yifan Z, Wenhui W. Analysing the current
status, hotspots, and future trends of technology management: Using
the WoS and scopus database. Heliyon [Internet]. 2023;9(9):e19922.
Rousseau R, Egghe L, Guns R. Becoming Metric-Wise: a bibliometric guide
for researchers. United Kingdom: Chandos Publishing; 2018.
Aria M, Cuccurullo C. Bibliometrix: an R-Tool for comprehensive
science mapping analysis. J Informetr [Internet]. 2017;11:(4)959-75.
Klochkova OA, Kurenkov AL. Priorities and goals of botulinum toxin
a treatment in cerebral palsy. Zh Nevrol Psikhiatr Im S S Korsakova
[Internet]. 2019;119(2):118-124
Pellett S, Yaksh TL, Ramachandran R. Current status and future
directions of botulinum neurotoxins for targeting pain processing.
Toxins (Basel) [Internet]. 2015;7(11):4519-63.
Pirio Richardson S, Altenmüller E, Alter K, Alterman RL, Chen R,
Frucht S, et al. Research priorities in limb and task-specific dystonias.
Front Neurol [Internet]. 2017;8:170.
Wong C. The effect of botulinum toxin-A on chronic muscle-related
pain in cerebral palsy. Front Neurol [Internet]. 2022;13:936625.
Ip AH, Phadke CP, Boulias C, Ismail F, Mills PB. Practice patterns of
physicians using adjunct therapies with botulinum toxin injection
for spasticity: a Canadian multicenter cross-sectional survey. PM R
[Internet]. 2021;13(4):372-78.
Yao D, O'Flynn LC, Simonyan K. DystoniaBoTXNet: novel neural
network biomarker of botulinum toxin efficacy in isolated dystonia.
Ann Neurol [Internet]. 2023;93(3):460-71.
Lozada-Martinez ID, Ealo-Cardona CI, Marrugo-Ortiz AC, Picón-Jaimes
YA, Cabrera-Vargas LF, Narvaez-Rojas AR. Meta-research studies in
surgery: a field that should be encouraged to assess and improve the
quality of surgical evidence. Int J Surg [Internet]. 2023;109(6):1823-4.
Lozada-Martinez ID, Lozada-Martinez LM, Fiorillo-Moreno O. Leiden
manifesto and evidence-based research: are the appropriate
standards being used for the correct evaluation of pluralism, gaps and
relevance in medical research? J R Coll Physicians Edinb [Internet].
;54(1):4-6.
Loannidis JPA. Meta-research: the art of getting it wrong. Res Synth
Methods [Internet]. 2010;1(3-4):169-84.
Loannidis JPA, Fanelli D, Dunne DD, Goodman SN. Meta-research:
evaluation and improvement of research methods and practices.
PLoS Biol [Internet]. 2015;13(10):e1002264.
Loannidis JPA. Meta-research: why research on research matters.
PLoS Biol [Internet]. 2018;16(3):e2005468.
Lozada-Martinez ID, Lozada-Martinez LM, Cabarcas-Martinez A, RuizGutierrez FK, Aristizabal Vanegas JG, Amorocho Lozada KJ, et al.
Historical evolution of cancer genomics research in Latin America:
a comprehensive visual and bibliometric analysis until 2023. Front
Genet [Internet]. 2024;15:1327243.
Lee A, Higginbotham G, Davies P, Young A. Research priority setting
in plastic and reconstructive surgery: a systematic review. J Plast
Reconstr Aesthet Surg [Internet]. 2023;76:148-59.
Eaves FF 3rd, Rohrich RJ, Sykes JM. Taking evidence-based
plastic surgery to the next level: report of the second summit on
evidence-based plastic surgery. JAMA Facial Plast Surg [Internet].
;15(4):314-20.
Zurita-Cruz JN, Márquez-González H, Miranda-Novales G, VillasísKeever MÁ. Estudios experimentales: diseños de investigación para la
evaluación de intervenciones en la clínica. Rev Alerg Mex [Internet].
;65(2):178-86.
Knight KL. Study/experimental/research design: much more than
statistics. J Athl Train [Internet]. 2010;45(1):98-100.
Lee WJ. Research, plastic surgery, and archives of plastic surgery.
Arch Plast Surg [Internet]. 2017;44(5):359-60.
Cheng F, Ma Y, Uzzi B, Loscalzo J. Importance of scientific
collaboration in contemporary drug discovery and development: a
detailed network analysis. BMC Biol [Internet]. 2020;18(1):138.
Chiang G, Umbuzeiro G, Lo Nostro F. Latin America: Knowledge
diversity for a sustainable future. Integr Environ Assess Manag
[Internet]. 2023;19(3):613-14.
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